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Aging Shrinks the Brain

In most people, their brains get smaller as they age. It is not so much that neurons die but that their terminals and synaptic junctions shrivel. A known cause is the over-secretion of cortisol by stress, but perhaps there are also other age-related causes. However, shrinkage with age is not inevitable. Certain people are "super-agers," defined as adults over 80 with memory at least as good as normal middle-aged adults. A usually reliable index for decline in memory ability is the degree of brain shrinkage, specifically cortical volume. Brain-scan studies show that super-agers have thicker layers of cortex than do others of the same age. Thus, their cortex has not shrunk as much as average elderly or they had more to start with. It is possible that something about the lifestyle of super-agers protected them from brain atrophy. It is not convenient to know how much cortical volume the elderly had in their youth. But the second option has been tested in a study that compared th...

Teaching Children to Be Honorable

No one is born honorable. If you doubt me, just watch little kids at play. Scholarly research has confirms the point. Michael Lewis, a prominent psychologist at Rutgers, has conducted many studies of how children naturally lie and deceive and are even encouraged to do so by well-meaning parents. Certain ways of expressing emotion are taught to be acceptable while others are not. One experiment, for example, showed that children are usually taught to express sadness when their mother leaves them with a baby sitter. But the reality was that children were not sad and recovered quickly when the mother left. Other examples are how children are taught to express responses to minor insults or injuries. Some kids are taught that it is alright to over-react. Lewis and his colleagues conducted some classical experiments in young children that revealed how their tendency for false behavior changed with age. They secretly videotaped children in an honesty test in which they were told not to peek a...

Do We See the World Like a Movie?

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We have the feeling that we experience the world like a continuously sampled data stream. If we perceive multiple objects of events seemingly at the same time, we may actually be multiplexing the several data streams; that is, we take a sample from one data stream, switch to take a sample from the next stream and so on — all on a millisecond time scale. But another possibility is that we perceive objects and events like a movie frame, where the brain takes working-memory snapshots and plays them in succession. Like still frames in a movie, if played at a high-enough speed, the frames will blend in our mind to give the illusion of continuous monitoring. In either case, we have to account for working memory. That is, we can only hold a small amount of information in our working memory at any one instant, as in being able to dial a seven-digit phone number you just looked up. In the phone number case, does our brain accumulate and buffer the representation of each integer until reaching t...

Is Your Brain Older Than You Are?

"You are as old as you think you are," the saying goes. Well, not quite. You, that is the inner you in your brain, is as old as your brain is. But your brain age may or may not correlate with chronological age. The other day at my gym workout, I again saw a young black guy, built like Captain America, whose workout schedule sometimes overlaps with mine. We had not met, and out of the blue he came up to me and said, “You are my inspiration. You inspire me to be able to work out like you when I get your age.” Wow! I inspire somebody! Then my balloon popped when I realized that he knew I was old just by looking at me. My body may not look like I’m 83, but I guess hair loss and the lines in my face betray me. The point of this story is that the bodily organs do not have the same rate of aging. Skin ages rather conspicuously in most older people. Specific organs may age at different rates depending on what they have been exposed to, for example skin and sun, liver and alcohol, lun...

Mental Down-time Affects Memory

Research has shown that recent experiences are reactivated during sleep and wakeful rest. This "downtime" recall of memories is part of the process for consolidating long-term memory and serves as memory rehearsal that can strengthen the memory. Thus, the old saying, "all work and no play makes Jack a dull boy," might be re-framed, "all work and no rest makes Jack a poor learner." To expand on this idea, a study was conducted to test whether this memory enhancing effect of mental downtime applied to new learning of related material. In other words, does downtime help form memories for new experiences as well as it does for recent past experiences? The researchers hypothesized that the degree to which memory processes are engaged during mental downtime determines whether or not prior knowledge promotes or interferes with new learning. To test this idea, human adults were trained on learning face-object pairs over four repetitions. This initial learning was ...

A Possible Remedy for Depression

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In the United States, some 5-7% of the population is clinically depressed in any given year. Over a lifetime, there are high odds that each of us has been depressed at some point. Sadly for seniors, the likelihood can increase with age. A new treatment approach that combines mindfulness meditation and aerobic exercise seems promising. In a recent study, 22 clinically diagnosed patients with major depressive disorder were put on a treatment regimen that begins with 30 minutes of mindfulness meditation and is followed by 30 minutes of aerobic exercise. Thirty people without depression symptoms served as a comparison group. In the meditation session, patients were told to focus on the present moment and their slow, deep breathing and excluding all mind-wandering and intrusive thoughts. Exercise was on a treadmill or stationary bicycle. At the end of eight weeks, patients were assessed again for depression symptoms, and symptoms decreased on average by 40%. An electrically evoked brain-wav...

Memory Training Produces Lasting Effects

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I first got interested in memory training at age 15 when my dad was a salesman for the Dale Carnegie leadership course, which included a section on memory training. My dad taught me some tricks that enabled me to memorize the gist of what was on every page of a magazine, by page number, in 30 minutes. I used to put on demonstrations for prospective enrollees. Before the recruitment meeting started, the leader would tell the audience, "Everybody see Billy here. Stand up Billy. I am going to give him this latest magazine issue, which he has never seen, and let him study it for 30 minutes. Then we will interrupt the meeting and you can ask him what is on any given page. Or you can tell him what is on a page, and he can tell you the page number." To my own astonishment, I could do it and it was not that hard. The basic gimmick was first to memorize a number code that converted page numbers into a visual image. For example, the code for 20 was "noose," as in a hangman...